Pharmacology and mechanism of effect:
L-carnitine is made of lysine and methionine amino acids and releases energy from fat cells. The role of L-carnitine is the transfer of high-chain fatty acids from cytosol to mitochondria during the process of fat metabolism and energy production.
On the other hand, the use of fats as a source of energy saves the muscle glycogen consumption and, by preserving glycogen stores, can delay the onset of exercise fatigue. L-Carnitine can help increase fat burning in the body, increase the energy level and reduce the weight.
It also seems that the presence of L-carnitine is needed to improve cardiac function. Research has shown that abnormal cardiac function and abnormal cardiac arrhythmias have been greatly reduced and improved after 45 weeks of consuming 4 grams of L-carnitine per day in diabetic patients who, besides high blood pressure, suffered from cardiovascular disease. . L-carnitine does not prevent carnitine deficiency in muscle building programs (muscle building up) and muscle cramps in hemodialysis and helps improve heart function. It also has antioxidant effects and helps to improve heart disease, such as heart attacks, cardiovascular failures, angina, peripheral vascular disease, cerebrovascular disease, and neurological disorders. L-carnitine improves Alzheimer’s disease and cognitive impairment, kidney disease and dialysis and also improves chronic fatigue syndrome. A remarkable point in this article is its effect on the fertility of men who are defective for unknown reasons in sperm production. Carnitine acts as the main source of energy for sperm and protects the membrane against damage from oxygen free radicals and increases the number of sperm and its mobility. Many bodybuilders use this supplement for the following reason: It boosts muscle and muscle. Increases energy. Helps burn fat and helps prevent muscle fatigue.
Side effects: One of the side effects of L-carnitine is insomnia, digestive disorders such as infertility, dizziness, diarrhea, abdominal pain and despondency. Serious complications include palpitations, increased blood pressure, seizures, and fever. In some people, the smell of urine, breath and sweat may be due to the formation of a metabolite of trimethylamine in the form of a fishing smell.
Precautions and adverse reactions:
- L-carnitine may make hypothyroidism worse.
- L-Carnitine is not recommended for people with a history of seizure.
- Patients with severe renal insufficiency should not take long-term high doses of this supplement because of the accumulation of trimethylamine and trimethylamine-N-oxide metabolites.
- Not for Use by pregnant or lactating women.
- The use of this supplement in lactating women is not a problem in the physician’s discretion.
- L-carnitine is not a problem if it is given in children at a dose that is approved for a short period.
- Keep out of reach of children
L-carnitine interacts with warfarin and increases the risk of bruising and bleeding. L-carnitine interferes with Acenocoumarol, which slows the process of blood clotting.
Storage: In below 30 °C and dry & dark place.